Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to increase natural growth hormone (GH) production and subsequent IGF-1 levels. It is best known for its ability to reduce visceral abdominal fat while preserving lean muscle mass. Unlike exogenous growth hormone, Tesamorelin works by enhancing the body's natural GH pulse patterns, making it a popular research peptide for body composition, recovery, and metabolic health.
Common Research Dosing Protocol:
1-2 mg daily
Most common protocol: 2 mg daily
Administered 5-7 days per week
Typical cycle length: 12-26 weeks
Administration:
Subcutaneous injection
Best administered on an empty stomach
Common timing: 30-60 minutes before bed or first thing in the morning
Avoid eating for approximately 30-60 minutes before and after administration when possible
Storage:
Refrigerate at 36-46°F (2-8°C) after reconstitution
Protect from light
Do not freeze
Use sterile technique for all withdrawals
Notes:
Tesamorelin is frequently researched for:
Reduction of visceral fat
Improved body composition
Increased IGF-1 levels
Recovery and tissue repair
Preservation of lean muscle mass during fat loss
It is commonly stacked with Ipamorelin to enhance growth hormone signaling. A typical combination protocol is:
Tesamorelin: 2 mg daily
Ipamorelin: 200-300 mcg daily
For someone in your situation, Matthew, with a focus on reducing abdominal visceral fat while maintaining muscle during a calorie deficit and resistance training, Tesamorelin is one of the more targeted peptides because its strongest human data relates specifically to visceral adipose tissue reduction rather than simply overall weight loss. Most studies show measurable changes emerging after 8-12 weeks, with continued improvements through 6 months of consistent use.
Tesamorelin is a synthetic growth hormone-releasing hormone (GHRH) analog that stimulates the pituitary gland to increase natural growth hormone (GH) production and subsequent IGF-1 levels. It is best known for its ability to reduce visceral abdominal fat while preserving lean muscle mass. Unlike exogenous growth hormone, Tesamorelin works by enhancing the body's natural GH pulse patterns, making it a popular research peptide for body composition, recovery, and metabolic health.
Common Research Dosing Protocol:
1-2 mg daily
Most common protocol: 2 mg daily
Administered 5-7 days per week
Typical cycle length: 12-26 weeks
Administration:
Subcutaneous injection
Best administered on an empty stomach
Common timing: 30-60 minutes before bed or first thing in the morning
Avoid eating for approximately 30-60 minutes before and after administration when possible
Storage:
Refrigerate at 36-46°F (2-8°C) after reconstitution
Protect from light
Do not freeze
Use sterile technique for all withdrawals
Notes:
Tesamorelin is frequently researched for:
Reduction of visceral fat
Improved body composition
Increased IGF-1 levels
Recovery and tissue repair
Preservation of lean muscle mass during fat loss
It is commonly stacked with Ipamorelin to enhance growth hormone signaling. A typical combination protocol is:
Tesamorelin: 2 mg daily
Ipamorelin: 200-300 mcg daily
For someone in your situation, Matthew, with a focus on reducing abdominal visceral fat while maintaining muscle during a calorie deficit and resistance training, Tesamorelin is one of the more targeted peptides because its strongest human data relates specifically to visceral adipose tissue reduction rather than simply overall weight loss. Most studies show measurable changes emerging after 8-12 weeks, with continued improvements through 6 months of consistent use.